Objectives: to compare in-hospital mortality from cardiogenic shock after myocardial infarction in patients with multivessel versus one vessel coronary disease.
Methods and results: This was an observational, cross-sectional, comparative, retrospective study. We included patients with acute myocardial infarction and cardiogenic shock. They were divided into three groups: one vessel, two vessel and three vessel coronary artery disease, looking for in-hospital death, obtaining data from clinical records. An analysis of the demographic, clinical, laboratory and angiographic variables was performed using descriptive and inferential statistics, performing student's T test and multivariate analysis using logistic regression.
We included 113 patients with a mean age of 65.1 years (+/-10.9), 83 men (73.5%). We’ve obtained 35 patients with one vessel (30.9%), 39 with two vessel (34.5%) and 39 with three vessel coronary disease (34.5%). The overall in-hospital mortality of cardiogenic shock was of 55.8% and of 51.4%, 56.4% y 59% for one, two and three vessels respectively with no statistical difference. The number of diseased vessels did not predict mortality (OR: one vessel disease: 1.04 CI 95% [0.41 - 2.68] p=0.93; two vessel: 0.54 CI 95% [0.20 - 1.47] p=0.23; three vessel disease: 1.48 CI 95% [0.59 - 3.74] p=0.40). Acute kidney injury (OR 4.24 CI 95% [1.89-9.51] p=<0.001), liver damage (OR 3.18 CI 95% [1.39 - 7.24] p=0.006) and lactate levels (OR 1.37 CI 95% [1.15-1.61] p=<0.001) were found to be in hospital-death predictors in cardiogenic shock. The use of intraaortic ballon pump, during or after the percutaneous coronary intervention, had no statistical significance for in-hospital mortality.  
Conclusions:  we did not find statistical difference in in-hospital mortality between cardiogenic shock in acute myocardial infarction with one vessel and multivessel coronary disease, neither with the use of intraaortic balloon pump.